Phentermine is a prescription drug for weight loss. It works by affecting certain neurotransmitters and stimulating the hypothalamus part of the brain causing the release of norepinephrine which suppresses the appetite. It also works outside the brain by causing the release of adrenaline and epinephrine which causes fat cells to break down stored fat inside the body.
Phentermine has been around for many, many years. It was first approved by the Food and Drug Administration (FDA) in 1959. There were two forms of Phentermine that became available in the United States, the first was Phentermine resin which became available in 1959 and then in the early 1970′s Phentermine Hydrochloride was made available. It is used by doctors to treat patients for obesity and is a short term treatment option. It is one of the most common appetite suppressant medications prescribed by doctors. Approximately 50% of all appetite suppressant medications prescribed by doctors is Phentermine.
Two pharmaceutical companies that sell Phentermine, are Medeva Pharmaceuticals, with its brand name Lonamin, and Gate Pharmaceuticals with the brand Apidex-P. It is also available in the generic form which is called Phentermine. King Pharmaceuticals for SmithKline Beecham sold Phentermine under the name of Fastin, but it was removed from the market in 1998. Since Phentermine is an older medication there has not been any new clinical studies done. In 1973 the FDA approved another appetite suppressant drug by the name of Fenfluramine for treatment of obesity. Doctors began writing prescriptions combining these two strong appetite suppressants together to make an even more powerful diet drug. That is when the drug by the name of Fen-Phen became well known.
In 1992 there was a study done on Fen-Phen by a doctor and his colleagues at Rochester University stating that the use of Fen-Phen was better for weight loss than dieting or exercise, and that there were no immediate side effects. This combination of Phentermine and Fenfluramine became and overnight hit and millions of prescriptions were written for patients. The FDA never approved the combination of these drugs, but since they were individually FDA approved doctors could write prescriptions all they wanted.
Dexfenfluramine was another appetite suppressant approved by the FDA in 1996 for obese patients. Phentermine was then combined with Dexfenfluramine which created Dexfen-Phen. This combination was not approved by the FDA either. This too, like Fen-Phen, became a very popular weight loss medication. Neither one of these drug combinations were ever tested for safety. In 1997 the Mayo Clinic reported 24 cases of heart valve disease in which all 24 cases the patients had used the drug Fen-Phen. The FDA issued a Public Health Advisory on July 28, 1997 after the Mayo Clinic evaluations. Evaluations of patients using Fenfluramine or Dexfenfluramine also showed 30% abnormal valve disease. In September of 1997 the FDA asked patients to stop taking these drugs and requested the drug manufacturers to voluntarily withdraw these two medications from the market.
The newest drug combination involving Phentermine is called Phen-Pro. Phen-Pro is a combination of Phentermine and Prozac or another antidepressant such as, Zoloft, Effexor, Celexa, Luvox or Trazadone. The antidepressants used in this method are not used for depression, but to make the effectiveness of Phentermine work better and for a longer period of time. This is once again another drug combination that is not approved by the FDA however since they are individually approved by the FDA, doctors can write prescriptions for patients to take these two medications together. Phentermine is usually prescribed for a patient that has a health related issue due to being obese. It is considered a controlled substance and therefore cannot be purchased without a prescription.
Phentermine is one of many types of phenythylamine drugs. Phentermine, like other phenythylamines is used as a neurotransmitter for the human brain. Phentermine is specifically used as an appetite suppressant as it can modify the psychological cravings for food. The drug is often recommended to overweight and obese individuals whom are looking for a short term weight loss method. If you are overweight to the extent that you are at risk of health issues as a result of your weight then the use of phentermine is definitely recommended.
Many different medications modify the chemical process within the human brain. A few examples are stimulants and anti-depressants which both modify the messages sent through the neurotransmitters. If you are using phentermine then the messages sent through the neurotransmitters will be modified to suppress your appetite. The modifications to your neurotransmitters can cause a decreased hunger or craving for food and the ability to get full off a smaller amount of food. Some individuals may even have a lower amount of neurotransmitters and by using Phentermine you can increase the amount of them. Low levels of neurotransmitters can cause various health issues such as depression, anxiety, and obesity. As the use of Phentermine could combat the low levels of neurotransmitters it could also treat those problems. However, it is important to know that Phentermine is a drug that is only safe to use in the short term. Even if you get amazing results from the drug you should not continue using it for the long term as there could be negative results from doing so.
Phentermine will modify the hypothalamus gland. This gland is located within the central nervous system of the human brain. The drug will interfere with the messages that are being sent through neurotransmitters and the hypothalamus gland. The interference with the message will modify it to tell your brain something else. In the case of using phentermine it will tell your brain that it thinks that you are full and not hungry.
When using phentermine, your leptin levels will be increased dramatically. Leptin is a hormone which is sent out of fat cells. It is used to manage the weight of the human body. It also plays a role in the hypothalamus gland. By the modification of the leptin levels occurring you will have a decreased appetite. During this time you will be less interested in eating and it will take less food to get you full. At the same time your body will be burning fat from adipose tissues. These are tissues which are primarily used to store body fat.
People that use phentermine may notice side effects which are similar to the side effects of speed, uppers, and similar drugs. Generally, phentermine use will provide a slightly euphoric feeling and can provide excessive energy which may not have been existent before you started using the drug. Due to the benefits that the drug has there are many people that want to continue using it for long periods of time but as already stated this is a dangerous thing to do.
The severe side effects are usually only noticed if you take a high dose of the drug. There are many common side effects of phentermine that you should become informed about. You can look these up online or speak with your doctor to find out about all of them. To give you an idea, some of the common side effects of phentermine include insomnia, feeling nervous, irritable, and experiencing panic attacks. Withdrawal symptoms may even be experienced if you attempt to stop using phentermine suddenly. It is recommended that you slowly lower your dosage of phentermine until you can completely come off the drug as it is an addictive drug to use.
There are many scary side effects associated with phentermine. As it can do a lot of damage and can cause serious problems with your health it would not be recommended unless it is absolutely needed. You have to make sure that you do not allow yourself to become dependent on the drug. You may like the results that it provides you but you cannot keep using the medication after your short treatment phase is over. You should speak with your doctor before using phentermine so you can get all the information on the drug and be able to use it as safely as possible.