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Acomplia is a weight loss drug that is specifically designed to help those who are obese or heavily overweight to reach a weight that is considered healthy. It is able to block receptors in the body’s central nervous system that can actually help you to control those feelings of hunger. It has yet to be approved by the FDA for use within the United States, although it has been granted market authorisation in 40 countries and is currently being sold in 20 countries throughout the world. The reason for this delay in approval by the FDA is caused by the potential links that Acomplia has to depression and suicidal tendencies. Acomplia can best be described as a branded version of the generic medication known as rimonabant.

The drug that has been branded Acomplia uses rimonabant as its active ingredient however rimonabant has yet to receive FDA approval in the United States. Should the Food and Drug Administration (FDA) eventually approve this drug is will be sold under the name of Zimulti in the United States. As mentioned, Acomplia will work by blocking the CB1 receptors in the central nervous system. These receptors can also be found in the fat tissue known as adipocytes. Acomplia is the first drug of its type to be approved anywhere in the world.

Acomplia has mainly been prescribed as a diet aid for people who do are considered heavily overweight and obese. However it is important to realise that the drug must be used in conjunction with a low-calorie diet and regular exercise, and in no way supersedes these. You will need to continue treatment with Acomplia to maintain any weight loss, but unfortunately the long-term effects of this drug are still unknown. Acomplia should only ever be prescribed to obese patients who may suffer from associated risk factors such as type II diabetes or dyslipidaemia. As mentioned, a healthy and regulated diet and exercise program should also be followed.

There have been numerous clinical studies that have suggested that there is a strong link between the use of rimonabant or Acomplia and the development of depression. In actual fact the depression may be so severe that it could lead to suicidal actions and tendencies. Therefore if you have suffered from a history of major depressive illness it is not advisable that you take Acomplia. Additionally if you are currently taking antidepressants or have an uncontrolled psychiatric illness, Acomplia should once again be avoided. If you are currently undergoing rimonabant therapy and you are diagnosed with depression or a psychiatric illness, then treatment should be stopped immediately.

Acomplia should never be taken by patients:

  • Who are breastfeeding – Should you become pregnant or plan to become pregnant and are taking Acomplia, you must inform your doctor immediately
  • Who are allergic to either rimonabant or any of the other active ingredients that are found in Acomplia
  • Who suffer from galactose intolerance or have problems with glucose absorption

Additional care should be taken when prescribing Acomplia if you are:

  • uffering with a hepatic impairment
  • suffering with a renal impairment
  • elderly
  • taking medications such as clarithromycin, etoconazole, itaconazole, nefazodone, ritonavir or telithromycin

There are also various side effects of taking Acomplia and these may include: anxiety, anorexia, depression, diarrhoea, nausea, vomiting, dry mouth, irritability, impaired attention, impaired memory, nervousness and sleep disorders.

It is recommended that you never take more than one 20 mg tablets of Acomplia per day. However should you ever overdose you may report symptoms such as headache, fatigue, insomnia and euphoria. If ever you suspect that somebody has overdosed on Acomplia it is important to contact medical assistance immediately, ensure that you monitor heart activity and keep all airways clear.

Another potential use of the drug rimonabant is an aid to quit smoking. It already has the name “the munchies drug” as it is believed to have the same effect as marijuana, but completely in reverse. It is said to curb your craving for nicotine as well as suppressing your appetite. One of the major worries of smokers looking to quit is the likelihood that they may put on weight. Nicotine has been known to suppress appetite and additionally raise blood sugar levels. Unfortunately once nicotine is completely eradicated this can lead to extreme hunger, and eventually putting on weight.

Acomplia has been touted as the perfect drug for smokers looking to give up the habit. Not only is it able to deter smoking, it may even fend off any weight gain. This almost appears to be the perfect marketing ploy, but should be approached with extreme caution. The fact that rimonabant has certain links to depression, and the fact that it is yet to receive FDA approval may be all the evidence you need to avoid this drug without prior medical consent.

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